Chuck and Blair make a bet to choose the perfect date for each other for the annual Snowflake Ball. Lexi has her sights set on Dan leaving Serena confused with her feelings. Nate and Vanessa are forced to be together leaving their emotions and friendship in danger of being burnt.

For Gaby and Carlos, injuries sustained in the fire lead to a fortunate discovery. But for most, the consequences are less forgiving. Lynette and Tom vow to protect son Porter at any cost. Susan must learn to let go of the man she loves. Orson’s attempt at a good night’s sleep puts Bree in a most precarious, though amusing, position on the day of her big cooking demonstration.

Brennan’s father Max lands a teaching position at the Jeffersonian. When he ends up helping out with the murder case at hand, Brennan is noticeably bothered by his sudden presence in her professional life.

A Massive Dynamic employee leaps to his death after hallucinating a butterfly attack. Agent Scott proves useful in investigating the case, but a frustrated Olivia wants to remove him from her consciousness once and for all. Meanwhile, Peter deals with some enemies from his past

A man takes over Cuddy’s office and holds House, Thirteen, and several patients hostage. His demand? A diagnosis. The man forces Thirteen to act as a guinea pig for his treatments and House has to end the standoff before a SWAT team opens fire.

Sara takes a hostage in a bid to secure Scylla. Michael and Lincoln finally meet the General while one of their members switches allegiance.

Brooke is shocked to find out that Samantha is in her room with a boy named Jack. Along with that, Julian asks her to make some clothes for the movie. Peyton tries to get Mia to focus on her follow-up album. Lucas is excited when he travels to Hollywood to meet the director of the movie. Meanwhile, Nathan gets the chance for a pro-basketball try-out. Haley takes Jamie to his school’s talent show and Millicent confronts Mouth about Gigi.

The dark eclipse plays havoc with all our heroes powers. Peter and Nathan go to Haiti to find the only person that can stop Arthur. Sylar and Elle are given orders to capture Claire.

Despite a not-so-triumphant return, the guys party it up in NYC. After getting a tip from Vince’s mom, E stalks Gus Van Sant to convince him to cast Vince in a role. Meanwhile, Vince reconnects with his high school sweetheart and Drama considers an investment opportunity.

Sookie finds a connection to the murders in Bon Temps. Jason finds a new goal in life. Bill temps fate continuing to find a way to rescue Sookie from harm. Sam is troubled by a familiar face from his past.